Exploring brain function in voice disorders like laryngeal dystonia and voice tremor
Understanding disorder-specific neural pathophysiology in laryngeal dystonia and voice tremor
This study is looking at how the brain helps people with laryngeal dystonia and voice tremor speak, using special brain scans to find out what’s happening in their brains during speech, so we can better understand these conditions and improve treatment options for those affected.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts Eye and Ear Infirmary NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10915598 on NIH RePORTER |
What this research studies
This research investigates how the brain controls speech production in individuals with laryngeal dystonia and voice tremor, two neurological disorders that affect the ability to speak. By using advanced brain imaging techniques, the study aims to identify specific patterns of brain activity that occur during speech and how these may differ from normal function. The goal is to understand the underlying causes of these disorders, which do not show clear physical abnormalities in the larynx. This knowledge could lead to better diagnosis and treatment options for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with laryngeal dystonia or voice tremor who experience difficulties in speech production.
Not a fit: Patients with voice disorders caused by clear physical abnormalities in the larynx may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients suffering from voice disorders.
How similar studies have performed: Previous research has shown promise in using brain imaging to understand neurological disorders, suggesting that this approach could yield valuable insights.
Where this research is happening
Boston, United States
- Massachusetts Eye and Ear Infirmary — Boston, United States (Active)
Researchers
- Principal investigator: Simonyan, Kristina — Massachusetts Eye and Ear Infirmary
- Study coordinator: Simonyan, Kristina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.