Exploring brain changes caused by addictive substances

Multi-Scale Imaging Core (MSIC)

['FUNDING_P30'] · TRUSTEES OF INDIANA UNIVERSITY · NIH-10898847

This study is looking at how drugs affect the brain in different ways, from tiny changes to how brain circuits work, to help us understand addiction better and find new ways to treat it, which could really help people struggling with substance use disorders.

Quick facts

Phase['FUNDING_P30']
Study typeNih_funding
SexAll
SponsorTRUSTEES OF INDIANA UNIVERSITY (nih funded)
Locations1 site (BLOOMINGTON, UNITED STATES)
Trial IDNIH-10898847 on ClinicalTrials.gov

What this research studies

This research investigates how addictive substances affect the brain at various levels, from molecular changes to circuit activity. By utilizing advanced imaging techniques, the project aims to uncover the underlying mechanisms of substance use disorders, including behaviors like compulsion and withdrawal. The Multi-Scale Imaging Core will provide researchers with access to cutting-edge equipment and training to analyze these changes in detail, ultimately contributing to better prevention and treatment strategies for addiction. Patients may benefit from insights gained through this research that could lead to new therapeutic approaches.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research include individuals affected by substance use disorders or those at risk of developing such conditions.

Not a fit: Patients who do not have a history of substance use or are not at risk for substance use disorders may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to innovative strategies for preventing and treating substance use disorders.

How similar studies have performed: Other research has shown success in using advanced imaging techniques to study brain changes associated with addiction, indicating that this approach is promising.

Where this research is happening

BLOOMINGTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.