Exploring bioactive molecules from the human microbiome
Systematic characterization of bioactive molecules from the human microbiome
This study is looking at how tiny molecules made by the bacteria in our bodies affect the way these bacteria interact with us, and it aims to find out how this knowledge could help improve health for people dealing with microbiome-related conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Princeton University NIH-funded |
| Lab location | 1 site (Princeton, UNITED STATES) |
| Project ID | NIH-11089300 on NIH RePORTER |
What this research studies
This research investigates how molecules produced by the human microbiome affect interactions between microbes and their human hosts. By using advanced computational techniques and synthetic biology, the team will identify and analyze specific bioactive molecules that are crucial for these interactions. The research involves studying these molecules through various laboratory methods, including cell-based assays and animal models, to understand their roles in human health and disease. Patients may benefit from insights gained about how these molecules influence conditions related to the microbiome.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with conditions influenced by the microbiome, such as gastrointestinal disorders or infections.
Not a fit: Patients with conditions unrelated to the microbiome or those not affected by microbial interactions may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies that harness microbiome-derived molecules to improve health outcomes.
How similar studies have performed: Other research has shown promise in understanding microbiome interactions, suggesting that this approach could yield valuable insights.
Where this research is happening
Princeton, UNITED STATES
- Princeton University — Princeton, United States (Active)
Researchers
- Principal investigator: Abou Donia, Mohamed — Princeton University
- Study coordinator: Abou Donia, Mohamed
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.