Exploring advanced techniques for studying biomolecular structures
Official title: Center for Biomolecular Structure (CBMS)
Funded at Brookhaven Science Assoc-Brookhaven Lab · NIH-10946988 · Data updated 2026-11-12
This study is working on improving tools for scientists to better understand complex biological molecules, which could help in learning more about diseases and how to treat them.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brookhaven Science Assoc-Brookhaven Lab NIH-funded |
| Lab location | 1 site (Upton, United States) |
| Project start | September 1, 2019 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $4,592,873 |
| NIH project number | 2P30GM133893-06 |
| Project ID | NIH-10946988 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with conditions that involve complex biomolecular interactions, such as cancer or genetic disorders.
✕Less likely to help
Patients with conditions unrelated to biomolecular structures or those not requiring advanced biophysical techniques may not receive direct benefits from this research.
What this research studies
This research focuses on enhancing the capabilities of the Center for Biomolecular Structure (CBMS) at Brookhaven National Laboratory by integrating x-ray footprinting (XFP) with existing macromolecular crystallography and x-ray scattering techniques. The goal is to provide researchers with advanced tools that allow for high-throughput and systematic studies of complex biological molecules. By utilizing the bright and well-collimated x-ray beams from the National Synchrotron Light Source II, the project aims to support a diverse community of scientists in their hypothesis-driven research. Patients may benefit indirectly through advancements in understanding diseases at the molecular level.
Why it matters
Potential benefit: If successful, this research could lead to significant advancements in the understanding and treatment of various diseases by providing deeper insights into biomolecular structures.
How similar studies have gone: Other research has shown success with similar approaches in biomolecular studies, indicating a promising potential for breakthroughs in this area.
Where this research is happening
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Brookhaven Science Assoc-Brookhaven Lab
Upton, United States Active
Researchers
- Principal investigator: Mcsweeney, Sean — Brookhaven Science Assoc-Brookhaven Lab
- Study coordinator: Mcsweeney, Sean
Related research
Other NIH-funded projects on the same topics.
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Training researchers to effectively use biomolecular resources
This study is all about helping researchers get better at using the tools and resources at the Center for Biomolecular Structure by offering hands-on training, workshops, and helpful online guides, so they can make the most of what the center has to offer.
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Providing support for advanced structural biology technologies
This study is all about using advanced technology to help scientists better understand the tiny structures of proteins and other biological materials, which could eventually lead to new treatments for patients like you.
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Access to advanced X-ray technology for studying biological materials
This study is exploring new ways to use advanced X-ray technology to better understand how our bodies work and how diseases affect us, which could help improve diagnosis and treatment for patients like you.
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Advanced technology for studying biological molecules
This study is all about using special tools at a research facility to help scientists quickly and easily study the tiny structures of proteins and other biological materials, which can lead to new medicines and better treatments for diseases.
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Access to advanced synchrotron capabilities for biomolecular research
This study is all about helping scientists learn how to use advanced tools to look closely at the structures of important biological molecules, which can lead to better understanding of how our bodies work.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.