Exploring a new type of immune cell's role during viral infections
Transitional dendritic cells: identifying the origin and role of a novel innate immune population during viral infection
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-11011259
This study is looking at a special type of immune cell called transitional dendritic cells to see how they help our bodies fight off viral infections, which could lead to new ways to boost our immune responses against viruses.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-11011259 on ClinicalTrials.gov |
What this research studies
This research investigates a newly identified population of immune cells called transitional dendritic cells (tDCs) that play a crucial role in the body's response to viral infections. By using advanced techniques to analyze these cells at a single-cell level, the researchers aim to understand how tDCs contribute to activating T cells and producing antiviral responses. The study will also explore the developmental origins of these cells, which could provide insights into their function during infections. This knowledge may help in developing new therapeutic strategies to enhance immune responses against viruses.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with viral infections or those interested in understanding immune responses.
Not a fit: Patients with non-viral infections or those not engaged in immune response research may not benefit from this study.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for viral infections by enhancing the body's immune response.
How similar studies have performed: While the specific role of transitional dendritic cells is novel, similar research on dendritic cells has shown promising results in understanding immune responses.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: IDOYAGA, JULIANA — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: IDOYAGA, JULIANA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: burden of disease