Exploring a new treatment for Cannabis Use Disorder
Advancement of AEF0117 as a potential treatment for Cannabis Use Disorder: Preclinical toxicity and Clinical pharmacokinetic studies
This study is testing a new medication called AEF0117 to see if it can help people who want to reduce their cannabis use, and it includes both animal tests and trials with volunteers to make sure it's safe and works well.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10668477 on NIH RePORTER |
What this research studies
This research focuses on AEF0117, a novel medication aimed at treating Cannabis Use Disorder (CUD). It involves conducting safety and pharmacokinetic studies to evaluate how the drug behaves in the body and its potential effectiveness in reducing cannabis use. The research includes both animal studies and trials with human volunteers to ensure the medication is safe and effective before larger clinical trials. Patients may benefit from a new treatment option that could help manage their cannabis use.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Cannabis Use Disorder who are seeking treatment options.
Not a fit: Patients who do not have Cannabis Use Disorder or those who are not interested in pharmacological treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new, effective medication for individuals struggling with Cannabis Use Disorder.
How similar studies have performed: Previous studies have shown promising results with similar medications aimed at treating substance use disorders, indicating potential for success with this approach.
Where this research is happening
New York, United States
- New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC — New York, United States (Active)
Researchers
- Principal investigator: Levin, Frances Rudnick — New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC
- Study coordinator: Levin, Frances Rudnick
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.