Exploring a new therapy for healing diabetic foot ulcers
Assessment of CCL3 Therapy in Diabetic Wound Care
This study is looking at a new treatment to help heal diabetic foot ulcers by understanding how certain white blood cells work in these wounds, and it’s for people with diabetes who are dealing with slow-healing sores on their feet.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project ID | NIH-11142273 on NIH RePORTER |
What this research studies
This research investigates a novel therapy aimed at improving the healing of diabetic foot ulcers (DFUs), which are a significant complication of diabetes leading to amputations. The study focuses on understanding how neutrophils, a type of white blood cell, behave in diabetic wounds and how their impaired function contributes to infection and delayed healing. By examining the role of specific receptors on these cells, the research aims to identify ways to enhance their response to wounds, potentially leading to better healing outcomes for patients. Participants may receive a new treatment that targets these mechanisms to improve their wound healing process.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with diabetic foot ulcers who are at risk of infection and complications due to their condition.
Not a fit: Patients without diabetes or those who do not have diabetic foot ulcers may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for diabetic foot ulcers, reducing the risk of amputations and improving patients' quality of life.
How similar studies have performed: Previous research has shown promise in enhancing neutrophil function in diabetic conditions, suggesting that this approach may lead to meaningful advancements in wound care.
Where this research is happening
Davis, United States
- University of California at Davis — Davis, United States (Active)
Researchers
- Principal investigator: Shafikhani, Sasha H — University of California at Davis
- Study coordinator: Shafikhani, Sasha H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.