Exploring a new method for non-invasive brain stimulation
Official title: Advancing non-invasive brain stimulation: A CompreheNSive Study of Temporal Interference Mechanisms (CNS-STIM)
Funded at Emory University · NIH-10946265 · Data updated 2026-11-12
This study is exploring a new way to gently stimulate the brain using special electrical signals, which could help improve treatments for neurological conditions by better understanding how this technique works.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | August 14, 2024 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $378,453 |
| NIH project number | 1R01NS138733-01 |
| Project ID | NIH-10946265 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with neurological conditions that may benefit from non-invasive brain stimulation techniques.
✕Less likely to help
Patients with conditions that do not involve the central nervous system or those who are not suitable for electrical stimulation may not benefit from this research.
What this research studies
This research investigates Temporal Interference (TI), a novel technique for non-invasive brain stimulation that uses high-frequency electrical currents to stimulate specific areas of the brain. By applying two high-frequency signals simultaneously, the researchers aim to create a targeted stimulation effect deep within the brain. The study will involve monitoring neuronal activation in brain slices and live animals to understand how this method can effectively modulate brain activity. The goal is to fill existing knowledge gaps about TI's mechanisms and its potential applications in treating neurological conditions.
Why it matters
Potential benefit: If successful, this research could lead to improved non-invasive treatments for various neurological disorders.
How similar studies have gone: Previous research has shown promise with non-invasive brain stimulation techniques, but the specific approach of Temporal Interference is relatively novel and not extensively tested.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Gutekunst, Claire-Anne N — Emory University
- Study coordinator: Gutekunst, Claire-Anne N
Related research
Other NIH-funded projects on the same topics.
-
Administrative and Engagement Core for Breast Cancer Breakthrough in Kenya
A national effort in Kenya to speed up how we screen for breast cancer and connect women to treatment, using teamwork across institutions.
-
Collaborative research program to advance patient care
A multi-project research effort at Emory University aims to push forward medical knowledge that could help people with illnesses in the future.
-
Project-003: A multi-partner research program at Emory University
A multi-faceted NIH grant at Emory University aims to advance understanding in a focused area over several years to benefit patients with diseases or conditions connected to the research.
-
Project-002: advancing patient care through coordinated research at Emory
A multi-project NIH grant at Emory aims to translate findings into better care for people with a health condition by coordinating research efforts across teams.
-
Project-006: A Multidisciplinary Emory Initiative to Advance Medical Understanding
A multi-project NIH grant at Emory University aims to push forward medical knowledge in areas that could eventually help patients.
-
Project-005: A multi-component research effort at Emory University
A multi-part NIH grant from Emory University aims to advance understanding in a specific health area over several years with potential patient benefits in the future.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.