Expanding the collection of human genetic reference genomes
Center for Human Genome Reference Diversity
This study is working to create a bigger and better collection of human genomes to help scientists understand our genetic diversity, and it invites people to participate in sharing their samples to make this important research possible.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Santa Cruz NIH-funded |
| Lab location | 1 site (Santa Cruz, United States) |
| Project ID | NIH-10908090 on NIH RePORTER |
What this research studies
This research focuses on enhancing the Human Pangenome Project by increasing the number of human reference genomes from 350 to 550. It involves recruiting diverse samples and utilizing advanced telomere-to-telomere genome sequencing technologies to ensure high-quality genomic data. The project emphasizes ethical practices throughout the research process and aims to provide valuable resources for the genomics research community. Patients may be involved in the recruitment process, contributing to a more comprehensive understanding of human genetic diversity.
Who could benefit from this research
Good fit: Ideal candidates for participation are individuals from diverse genetic backgrounds who are willing to provide consent for their genomic data to be used in research.
Not a fit: Patients with rare genetic disorders that are not represented in the expanded reference genomes may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved genomic resources that enhance personalized medicine and disease understanding.
How similar studies have performed: Previous phases of the Human Pangenome Project have shown success in enhancing genomic resources, indicating a promising continuation of this approach.
Where this research is happening
Santa Cruz, United States
- University of California Santa Cruz — Santa Cruz, United States (Active)
Researchers
- Principal investigator: Miga, Karen Hayden — University of California Santa Cruz
- Study coordinator: Miga, Karen Hayden
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.