Expanding opioid treatment and HIV prevention in prisons and probation

Prison Interventions and HIV Prevention Collaboration

NIH-funded research Yale University · NIH-11396975

This project brings opioid agonist therapy and HIV prevention services to people who inject drugs in prisons and on probation in Eastern Europe and Central Asia.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-11396975 on NIH RePORTER

What this research studies

If you are incarcerated or on probation and use opioids or inject drugs, this project works to make it easier to get lifesaving opioid agonist treatment (like methadone or buprenorphine) and HIV prevention services where you are. The team builds on earlier pilots that used screening, brief counseling, and referrals, and they will train local staff and use a Project ECHO tele-mentoring model to support clinicians. The work focuses on real-world rollout across prisons and probation systems, using existing health staff and infrastructure so services can continue after the project ends. The goal is to link people leaving prison or under supervision to ongoing care to reduce HIV risk and overdose.

Who could benefit from this research

Good fit: People in prisons or under probation supervision in Eastern Europe and Central Asia who inject drugs or have opioid use disorder, especially those living with or at high risk for HIV, are the intended participants.

Not a fit: People who are not in criminal justice settings, who do not inject drugs or have opioid use disorder, or who live outside the targeted EECA countries are unlikely to benefit directly from this project.

Why it matters

Potential benefit: Could lower HIV transmission and improve access to sustained opioid treatment and follow-up care for incarcerated and probation populations.

How similar studies have performed: Earlier pilots in the region used SBIRT and a Project ECHO model and showed promise for scaling up opioid agonist therapy, but broader real-world implementation has not yet been completed.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.