Expanding genetic participation for Alzheimer’s in African and Hispanic communities
Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP)
This project collects DNA and health information from people of African and Hispanic ancestry to better understand Alzheimer’s risk in those communities.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-11380114 on NIH RePORTER |
What this research studies
You would be invited to share health information and provide a blood or saliva sample so researchers can study genetic risk for Alzheimer’s in people of African and Hispanic ancestry. The team uses community-sensitive outreach and retention methods to build trust and keep participants involved. Samples will be genotyped and combined into a large research resource to look for genetic differences that affect Alzheimer’s risk. The goal is to enroll and study roughly 13,000 diverse participants to improve discovery power.
Who could benefit from this research
Good fit: Adults of African or Hispanic ancestry, including people with Alzheimer’s or related dementias and unaffected volunteers who can give consent and provide a DNA sample and health information.
Not a fit: People who are not of the targeted ancestries or those expecting immediate clinical treatment from participation are unlikely to receive direct personal medical benefit.
Why it matters
Potential benefit: If successful, this work could reveal genetic factors that explain ancestry-related differences in Alzheimer’s risk and help improve diagnosis, risk prediction, and more equitable treatments for underrepresented groups.
How similar studies have performed: Earlier, smaller genetics studies in African American groups have found important differences (for example APOE and ABCA7), but larger and more diverse datasets are still needed to confirm and extend those findings.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Pericak-Vance, Margaret a. — University of Miami School of Medicine
- Study coordinator: Pericak-Vance, Margaret a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.