Expanding dementia research for Latino communities in Latin America and the US
Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat2)
This project brings together health records, brain scans, and genetic information from Latino people with Alzheimer’s disease, frontotemporal dementia, and healthy volunteers to learn how social and genetic factors shape dementia.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11480849 on NIH RePORTER |
What this research studies
If you join, you would be asked to share medical and cognitive information, give a blood sample for genetic testing, and have brain imaging when possible. The project enrolls 3,000 new participants (750 with Alzheimer’s, 750 with frontotemporal dementia, and 1,500 controls) and combines them with earlier ReDLat data and related datasets. Researchers compare people across Latin American countries (Argentina, Brazil, Chile, Colombia, Mexico, Peru) and Latino participants in the United States to study how socioeconomic conditions, genetics, and brain measures relate to dementia. The team uses whole genome sequencing, clinical exams, cognitive testing, and neuroimaging to build models tailored to Latino populations.
Who could benefit from this research
Good fit: Ideal candidates are adults of Latino heritage with a diagnosis of Alzheimer’s disease or frontotemporal dementia, or age-matched Latino controls willing to provide clinical information, blood for genetics, and (if able) brain imaging.
Not a fit: People who are not of Latino background, have other types of dementia not targeted by the project, are minors, or are unwilling/unable to provide samples or imaging may not directly benefit from this work.
Why it matters
Potential benefit: If successful, this work could improve diagnosis and develop more culturally and genetically tailored care for Latino patients with dementia.
How similar studies have performed: Related multimodal and genetic studies have clarified dementia causes in other populations, and this project builds on prior ReDLat work to apply those methods specifically to Latino groups.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Miller, Bruce L — University of California, San Francisco
- Study coordinator: Miller, Bruce L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.