Expanding dementia research for Latin American and Latino communities
Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat2)
This project combines brain scans, genetic tests, and life-history information to better understand Alzheimer’s disease and frontotemporal dementia in Latino people in Latin America and the U.S.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11470962 on NIH RePORTER |
What this research studies
If you join, researchers will collect medical information, cognitive testing, brain imaging, and genetic data from thousands of people including those with Alzheimer’s, frontotemporal dementia, and people without dementia. The project will enroll 3,000 new participants (750 with Alzheimer’s, 750 with frontotemporal dementia, and 1,500 controls) across Argentina, Brazil, Chile, Colombia, Mexico, Peru, and the U.S., and combine these with existing datasets. Scientists will look at how social and economic factors, family history, and genetic differences relate to symptoms and brain changes in Latino groups. The aim is to create models and tools that better reflect the diversity of Latino patients and could improve diagnosis and care.
Who could benefit from this research
Good fit: Adults who identify as Latino or who live in the participating Latin American countries or the U.S., including people diagnosed with Alzheimer’s disease or frontotemporal dementia and cognitively healthy volunteers, are ideal candidates.
Not a fit: People who are not Latino, who live outside the participating countries with no ability to travel, or who have unrelated neurological conditions may not directly benefit from this project.
Why it matters
Potential benefit: If successful, this work could lead to more accurate diagnoses and care approaches tailored for Latino people with dementia.
How similar studies have performed: This project builds on the original ReDLat work and related studies that have already provided useful insights into genetic and socioeconomic contributors to dementia in Latin American groups.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Miller, Bruce L — University of California, San Francisco
- Study coordinator: Miller, Bruce L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.