Expanding dementia knowledge and care for Latino communities
Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat2)
This project combines brain scans, genetic testing, memory and health information from Latino people with Alzheimer's and frontotemporal dementia and from people without dementia to better understand how social and genetic factors shape dementia.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11471020 on NIH RePORTER |
What this research studies
You would be asked to provide health and social background information, complete memory and thinking tests, have brain imaging, and give a blood sample for genetic analysis. The project plans to enroll 3,000 new participants (750 with Alzheimer’s, 750 with frontotemporal dementia, and 1,500 people without dementia) across Argentina, Brazil, Chile, Colombia, Mexico, Peru, and partner sites in the United States and will combine these with 3,000 existing participants. Researchers will link clinical, cognitive, neuroimaging, genetic, and socioeconomic measures to see how economic and social conditions and genetics interact with brain changes and symptoms. The aim is to build models that reflect the diversity of Latino populations to improve diagnosis and care that fit different social and genetic backgrounds.
Who could benefit from this research
Good fit: Ideal candidates are Latino adults from Argentina, Brazil, Chile, Colombia, Mexico, Peru, or Latino individuals in the U.S. who have a diagnosis of Alzheimer’s disease or frontotemporal dementia, as well as Latino adults without dementia serving as controls.
Not a fit: People who are not Latino, who have other unrelated neurological conditions, or who are seeking immediate therapeutic treatment rather than contributing to research records may not directly benefit from participation.
Why it matters
Potential benefit: If successful, this effort could lead to more accurate diagnoses and care approaches tailored to Latino populations and uncover genetic and social drivers of dementia that are currently underrecognized.
How similar studies have performed: Earlier ReDLat work and other genetic and neuroimaging studies in dementia have produced useful leads, but this larger, multi-country effort is a significant and somewhat novel expansion for Latino populations.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Miller, Bruce L — University of California, San Francisco
- Study coordinator: Miller, Bruce L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.