Expanding Alzheimer’s genetics data for African and Hispanic communities
Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP)
['FUNDING_OTHER'] · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · NIH-11380146
This project will enroll people from African, African American, African Caribbean, and Hispanic backgrounds, with and without Alzheimer’s, to build a large genetic resource that improves understanding of Alzheimer’s risk in these groups.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MIAMI SCHOOL OF MEDICINE (nih funded) |
| Locations | 1 site (CORAL GABLES, UNITED STATES) |
| Trial ID | NIH-11380146 on ClinicalTrials.gov |
What this research studies
You would be invited to join a large effort to collect health information and a DNA sample so researchers can study genetic contributors to Alzheimer’s in underrepresented communities. The team will use community-sensitive recruitment and retention approaches to reach Black, African, Caribbean, and Hispanic participants. Collected samples will be genotyped and combined into a shared resource to search for genetic risk differences linked to ancestry. The goal is to make genetic findings more accurate and relevant for people from these backgrounds.
Who could benefit from this research
Good fit: Adults of African, African American, African Caribbean, or Hispanic/Latino ancestry, with or without a diagnosis of Alzheimer’s disease, who can provide consent and a blood or saliva sample are ideal candidates.
Not a fit: People who are not from the targeted ancestral groups or who cannot or will not provide consent or biospecimens are unlikely to benefit directly from this project.
Why it matters
Potential benefit: If successful, this resource could lead to more accurate risk information and more inclusive targets for future treatments for people of African and Hispanic ancestry.
How similar studies have performed: Previous large genetic studies in European ancestry groups have identified important Alzheimer’s risk genes and smaller efforts in African American groups have found different risk signals, but large, diverse cohorts like this are still relatively new.
Where this research is happening
CORAL GABLES, UNITED STATES
- UNIVERSITY OF MIAMI SCHOOL OF MEDICINE — CORAL GABLES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PERICAK-VANCE, MARGARET A. — UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
- Study coordinator: PERICAK-VANCE, MARGARET A.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.