Exercise program to improve health in lung transplant candidates

XFIT: An Exercise-based Frailty Intervention in Lung Transplant Candidates

NIH-funded research University of California, San Francisco · NIH-10952296

This study is testing a special exercise program designed to help people waiting for a lung transplant feel stronger and healthier, so they can have better outcomes before and after their surgery.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-10952296 on NIH RePORTER

What this research studies

This research focuses on developing an exercise-based intervention aimed at reducing frailty in patients awaiting lung transplants. It recognizes that many candidates experience frailty, which can lead to higher risks of complications and mortality. The program will involve tailored physical activity and lifestyle modifications to enhance physical strength and overall health. By addressing frailty through exercise, the research aims to improve patient outcomes before and after transplantation.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals on the lung transplant waiting list who are identified as frail.

Not a fit: Patients who are not awaiting lung transplantation or those who do not exhibit signs of frailty may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the health and survival rates of lung transplant candidates.

How similar studies have performed: Previous research has shown that exercise interventions can effectively reduce frailty in older adults, suggesting a promising approach for lung transplant candidates.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.