Exercise and rehabilitation to slow age-related loss of mobility
Applied Physiology and Mechanisms
Seeing if exercise, activity-based training, and multi-part rehabilitation help older adults with mobility problems keep function and independence.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11134599 on NIH RePORTER |
What this research studies
If you're an older adult with limited mobility, this center supports projects that use exercise, activity-based programs, and combined rehabilitation to improve walking, strength, and day-to-day independence. Researchers will track physical performance, markers of inflammation and metabolism, and cardiometabolic health to understand how these programs change your body and ability to function. Some work will run parallel tests in animal models to learn the biological reasons behind any improvements. The aim is to turn those findings into practical rehab approaches that could help older people avoid further decline.
Who could benefit from this research
Good fit: Older adults with mobility limitations or disability following events like stroke, hip fracture, arthritis, peripheral arterial disease, or with chronic diseases such as diabetes or cardiovascular disease.
Not a fit: Younger people or those without age-related mobility problems are unlikely to benefit directly from these specific rehabilitation-focused efforts.
Why it matters
Potential benefit: Could help older adults preserve mobility, reduce disability, and lower the risk of further age-related health decline.
How similar studies have performed: Previous research shows exercise can reduce inflammation and improve function in older adults, but combining multi-modal rehab with parallel animal-to-human mechanism work is still being developed.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Ryan, Alice S. — University of Maryland Baltimore
- Study coordinator: Ryan, Alice S.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.