NIH-funded research NIH-funded research

Examining the safety of CNS stimulants in veterans with brain injuries

Official title: Understanding CNS Stimulant Use and Safety in Veterans with TBI

Funded at U.s. Dept/vets Affairs Medical Center · NIH-11099682 · Data updated 2026-11-12

This study is looking at how safe it is for veterans with traumatic brain injuries to use certain medications that help with focus and energy, and it hopes to find helpful information to improve their treatment.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionU.s. Dept/vets Affairs Medical Center
NIH-funded
Lab location1 site (Washington, United States)
Project startMay 1, 2023
Project endApril 30, 2027
Funding year2025
NIH project number5I01HX003552-03
Project IDNIH-11099682 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are veterans diagnosed with traumatic brain injury, particularly those who have been prescribed CNS stimulants.

Less likely to help

Patients without a diagnosis of traumatic brain injury or those not prescribed CNS stimulants may not benefit from this research.

What this research studies

This research investigates the use of central nervous system (CNS) stimulants in veterans who have experienced traumatic brain injury (TBI). It aims to understand the safety and potential risks associated with these medications, particularly given their association with substance use disorders. The study will analyze data from veterans' health records to assess the prevalence of CNS stimulant prescriptions and their effects on veterans with TBI. By focusing on this population, the research seeks to provide insights that could inform treatment guidelines and improve patient care.

Why it matters

Potential benefit: If successful, this research could lead to safer treatment options for veterans with TBI, reducing the risk of substance use disorders.

How similar studies have gone: This research addresses a novel question regarding CNS stimulant use in veterans with TBI, as similar studies have not been conducted previously.

Where this research is happening

  • U.s. Dept/vets Affairs Medical Center
    Washington, United States
    Active

Researchers

  • Principal investigator: Faselis, Charles J — U.s. Dept/vets Affairs Medical Center
  • Study coordinator: Faselis, Charles J

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.