Examining the link between the microbiome and heart disease in people with HIV
Multiomics analysis of the microbiome and subclinical cardiovascular disease in HIV infection
This study is looking at how the bacteria in your mouth might affect heart health for people living with HIV, and it will compare results from both HIV-positive and HIV-negative individuals to see what differences there are.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project ID | NIH-11003733 on NIH RePORTER |
What this research studies
This research investigates how the microbiome, particularly in the mouth, may influence cardiovascular disease in individuals living with HIV. By analyzing saliva samples and using advanced sequencing techniques, the study aims to identify specific bacteria and their functions that could be associated with heart health. The research will involve both HIV-positive and HIV-negative participants, allowing for a comparative analysis. The findings could lead to a better understanding of how microbiome changes affect cardiovascular health in HIV patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who are HIV-positive and those who are HIV-negative, particularly those with or at risk for cardiovascular disease.
Not a fit: Patients who do not have HIV or cardiovascular disease may not benefit from the findings of this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing cardiovascular disease in people living with HIV.
How similar studies have performed: Previous research has shown promising results in understanding the relationship between the microbiome and various health conditions, suggesting that this approach could yield valuable insights.
Where this research is happening
Bronx, United States
- Albert Einstein College of Medicine — Bronx, United States (Active)
Researchers
- Principal investigator: Wang, Zheng — Albert Einstein College of Medicine
- Study coordinator: Wang, Zheng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.