Examining the effects of substance use and mental health on HIV care outcomes

Unhealthy alcohol use, other drug use, and mental health disorders: comorbidity burden in people with HIV, gaps in treatment, and impact on the HIV care continuum

NIH-funded research Johns Hopkins University · NIH-10690634

This study looks at how drinking too much alcohol, using cocaine or opioids without a prescription, and dealing with depression and anxiety can impact the health of people living with HIV, with the goal of finding better ways to help those facing these challenges.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10690634 on NIH RePORTER

What this research studies

This research investigates how unhealthy alcohol use, cocaine use, non-prescribed opioid use, depression, and anxiety affect the health outcomes of individuals living with HIV. It aims to understand the prevalence and co-occurrence of these issues among patients receiving HIV care, as well as the challenges in identifying and treating them. By exploring the interactions between these conditions, the study seeks to improve treatment strategies and support for patients struggling with both HIV and substance use or mental health disorders.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV who also experience unhealthy alcohol use, drug use, or mental health disorders.

Not a fit: Patients who do not have HIV or do not experience substance use or mental health issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment approaches that enhance the health outcomes of individuals living with HIV who also face substance use and mental health challenges.

How similar studies have performed: Previous research has indicated that addressing comorbid substance use and mental health disorders can significantly improve health outcomes for individuals with HIV, suggesting that this approach has potential for success.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immuno-Deficiency SyndromeAcquired Immunologic Deficiency SyndromeAcquired Immunodeficiency Syndrome
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.