Examining the effects of pollutants on endometriosis in women's tissue
Investigating Mixtures of Pollutants and Endometriosis in Tissue (IMPLANT) Study
This study is looking at how certain harmful chemicals in the environment might affect the development and severity of endometriosis in women, by comparing tissue samples from those with the condition to those without, to help find better ways to prevent and treat it.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | George Mason University NIH-funded |
| Lab location | 1 site (Fairfax, United States) |
| Project ID | NIH-10747853 on NIH RePORTER |
What this research studies
This research investigates how exposure to certain environmental pollutants may influence the development and severity of endometriosis, a condition affecting many premenopausal women. By analyzing tissue samples from women undergoing surgery for endometriosis, the study aims to measure levels of specific harmful chemicals, known as PFASs and POPs, in both healthy and affected uterine tissues. The goal is to understand the relationship between these pollutants and the incidence and severity of endometriosis, potentially leading to better prevention and treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are premenopausal women diagnosed with endometriosis who are undergoing laparoscopic surgery.
Not a fit: Patients who are postmenopausal or do not have a diagnosis of endometriosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of endometriosis, potentially reducing pain and infertility for affected women.
How similar studies have performed: While there is limited research specifically linking PFASs and POPs to endometriosis, studies on environmental pollutants and other health conditions suggest that this approach could yield valuable insights.
Where this research is happening
Fairfax, United States
- George Mason University — Fairfax, United States (Active)
Researchers
- Principal investigator: Pollack, Anna Zulema — George Mason University
- Study coordinator: Pollack, Anna Zulema
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.