Examining the effects of exercise therapy on prostate cancer progression
Randomized Trial of Exercise Therapy on Markers of Progression in Localized Prostate Cancer:
This study is looking at how regular treadmill walking at home might help men with low-grade localized prostate cancer who are being closely monitored, to see if it can change their cancer in a positive way and possibly lessen the need for tougher treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10911176 on NIH RePORTER |
What this research studies
This research investigates how exercise therapy can impact men with low-grade localized prostate cancer who are under active surveillance. Participants will be randomly assigned to either an exercise therapy group, which involves home-based treadmill walking five days a week, or a usual care group that receives general physical activity advice. The study aims to determine if exercise can alter the molecular landscape of prostate cancer and potentially reduce the need for more aggressive treatments. The exercise sessions will be monitored through a telemedicine platform, ensuring participants receive guidance and support throughout the program.
Who could benefit from this research
Good fit: Ideal candidates for this research are men diagnosed with low-grade localized prostate cancer who are currently on active surveillance.
Not a fit: Patients with advanced prostate cancer or those who are not eligible for active surveillance may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a non-invasive method to manage prostate cancer progression and improve patients' quality of life.
How similar studies have performed: Previous research has shown promising results in using exercise as a therapeutic intervention for cancer patients, indicating potential for success in this approach.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Jones, Lee W — Sloan-Kettering Inst Can Research
- Study coordinator: Jones, Lee W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.