Examining lung blood vessel changes to improve outcomes in lung diseases
Pulmonary Vascular Pruning on Computed Tomography and Interstitial Lung Disease Outcomes
This study is looking at how special CT scans can help find changes in the tiny blood vessels in the lungs that might put people at risk for serious lung problems, like fibrosis and high blood pressure in the lungs, so we can catch these issues early and help patients feel better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11036393 on NIH RePORTER |
What this research studies
This research investigates how changes in the small blood vessels of the lungs, known as pruning, can be detected through advanced imaging techniques using CT scans. By analyzing existing imaging data and recruiting new patients, the study aims to identify individuals at risk for serious complications related to interstitial lung diseases (ILD), such as progressive lung fibrosis and pulmonary hypertension. The goal is to enhance early detection and treatment strategies for these conditions, ultimately improving patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with interstitial lung disease who have undergone CT scans.
Not a fit: Patients with interstitial lung disease who do not have CT imaging available or those with advanced disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier identification and treatment of patients at risk for severe lung complications, potentially improving their quality of life and survival rates.
How similar studies have performed: Previous research has shown that advanced imaging techniques can successfully identify vascular changes in lung diseases, suggesting a promising avenue for this approach.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Synn, Andrew — Beth Israel Deaconess Medical Center
- Study coordinator: Synn, Andrew
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.