Examining how threats and rewards affect anxiety and depression in young people from low-income backgrounds

Computational examination of RDoC threat and reward constructs in a representative, predominantly low-income, longitudinal sample at increased risk for internalizing disorders

NIH-funded research University of Michigan at Ann Arbor · NIH-10657487

This study is looking at how social and environmental challenges affect anxiety and depression in young adults, especially those from low-income families, to help understand their mental health better over time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-10657487 on NIH RePORTER

What this research studies

This research investigates the impact of social and environmental challenges on anxiety and depression in young adults, particularly those from low-income families. By analyzing data from a longitudinal study, researchers will identify patterns of behavior and emotional responses related to threats and rewards. The study aims to understand how these factors contribute to mental health issues over time, using advanced data analytics to create models that predict internalizing symptoms. Participants will be drawn from a diverse cohort, ensuring that findings are applicable to a wide range of individuals.

Who could benefit from this research

Good fit: Ideal candidates for this research are young adults from low-income backgrounds who may be experiencing or at risk for anxiety and depression.

Not a fit: Patients who are not from low-income backgrounds or who do not exhibit symptoms of anxiety or depression may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for anxiety and depression in vulnerable populations.

How similar studies have performed: Previous research has shown promise in using data-driven approaches to understand mental health constructs, indicating potential for success in this novel application.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.