Examining how neighborhood disadvantage affects cognitive aging and Alzheimer's risk in African American communities
Longitudinal Examination of Neighborhood Disadvantage, Cognitive Aging, and Alzheimer's Disease Risk in Disinvested, African American Neighborhoods
This study is looking at how living in less wealthy neighborhoods affects brain health and the chances of developing Alzheimer's disease in African Americans, by following over 1,100 people to see how things like stress and sleep problems play a role.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11248937 on NIH RePORTER |
What this research studies
This research investigates the impact of living in disinvested neighborhoods on cognitive aging and the risk of Alzheimer's disease among African Americans. By following a cohort of over 1,100 residents from two predominantly African American communities, the study aims to understand how factors like socioeconomic conditions, exposure to discrimination, and adverse childhood experiences contribute to cognitive decline. The researchers will analyze how these neighborhood factors influence health outcomes, particularly focusing on the role of stress and sleep disruption in mediating Alzheimer's risk.
Who could benefit from this research
Good fit: Ideal candidates for this research are African American adults living in historically disinvested neighborhoods.
Not a fit: Patients who do not reside in the targeted neighborhoods or who are not of African American descent may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to targeted interventions that improve cognitive health and reduce Alzheimer's risk in African American populations.
How similar studies have performed: Previous research has indicated that neighborhood factors significantly influence health outcomes, suggesting that this approach could yield valuable insights.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Dubowitz, Tamara — University of Pittsburgh at Pittsburgh
- Study coordinator: Dubowitz, Tamara
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.