Examining how genetics and environment affect heart health in rural and urban areas
Official title: Rural-Urban Differences in Polygenic Associations for Health and Health Behaviors
Funded at University of Colorado · NIH-10734666 · Data updated 2026-11-12
This study is looking at how living in a city versus the countryside affects heart health and whether our genes play a role in that, so we can better understand and improve heart health for everyone, no matter where they live.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado NIH-funded |
| Lab location | 1 site (Boulder, UNITED STATES) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $155,364 |
| NIH project number | 1R03AG080244-01A1 |
| Project ID | NIH-10734666 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals aged 21 and older living in rural or urban areas who may be at risk for cardiovascular health issues.
✕Less likely to help
Patients who do not reside in the United States or are under 21 years old may not benefit from this research.
What this research studies
This research investigates the differences in cardiovascular health risks between rural and urban populations, focusing on how genetic predispositions may influence these risks. By analyzing data from the National Longitudinal Study of Adolescent to Adult Health, the study aims to understand the relationship between genetic factors and health behaviors such as obesity, high cholesterol, hypertension, and diabetes. The research will create new genetic risk scores for hypertension and provide valuable insights for health policy aimed at addressing health disparities. Ultimately, the findings could help tailor interventions to improve cardiovascular health in different communities.
Why it matters
Potential benefit: If successful, this research could lead to more effective health policies and interventions that address cardiovascular health disparities based on genetic and environmental factors.
How similar studies have gone: While there is limited research on rural-urban health disparities, previous studies have shown promising results in understanding the impact of genetics on health outcomes.
Where this research is happening
-
University of Colorado
Boulder, United States Active
Researchers
- Principal investigator: Boardman, Jason D — University of Colorado
- Study coordinator: Boardman, Jason D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.