Examining how disruptions in sleep patterns during pregnancy affect substance use in offspring
Investigating the long-term effects of prenatal circadian rhythm disruption on substance use-related disorders
['FUNDING_OTHER'] · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · NIH-11245825
This study looks at how changes in sleep patterns during pregnancy, like those caused by shift work, might affect kids later in life, especially regarding their chances of developing substance use issues, and it aims to find ways to help families impacted by these changes.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS (nih funded) |
| Locations | 1 site (TOLEDO, UNITED STATES) |
| Trial ID | NIH-11245825 on ClinicalTrials.gov |
What this research studies
This research investigates the long-term effects of prenatal circadian rhythm disruptions on the likelihood of developing substance use disorders in offspring. It focuses on how environmental factors, such as shift work, can alter sleep patterns during pregnancy and subsequently impact the health and behavior of children as they grow. By studying both animal models and human populations, the research aims to uncover the mechanisms behind these effects and identify potential interventions. The study will measure various outcomes related to substance use and behavioral health in adults who were exposed to prenatal circadian disruptions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals under 21 years old who have a history of substance use and whose mothers experienced significant disruptions in their sleep patterns during pregnancy.
Not a fit: Patients who do not have a history of substance use or whose mothers did not experience circadian rhythm disruptions during pregnancy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for substance use disorders in individuals affected by prenatal circadian disruptions.
How similar studies have performed: Previous research has shown that circadian rhythm disruptions can lead to negative health outcomes, suggesting that this approach has potential for significant findings.
Where this research is happening
TOLEDO, UNITED STATES
- UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS — TOLEDO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DEPOY, LAUREN MARIE — UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS
- Study coordinator: DEPOY, LAUREN MARIE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.