Examining how circulating tumor cells contribute to racial differences in metastatic prostate cancer
Circulating tumor cell profiling for genomic contributors to racial disparity in metastatic prostate cancer
This study is looking at why Black men are more likely to have advanced prostate cancer than white men by examining special cancer cells in their blood, which could help find better treatments for them.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Thomas Jefferson University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10953253 on NIH RePORTER |
What this research studies
This research investigates the genetic and molecular factors that contribute to the higher rates of metastatic prostate cancer in Black men compared to their white counterparts. By utilizing circulating tumor cells (CTCs) as a non-invasive method, the study aims to analyze these cells to understand the unique genetic alterations that may be present in this population. This approach allows for a comprehensive view of the cancer's evolution and characteristics without the need for difficult tissue biopsies. The findings could lead to better-targeted treatments and improved outcomes for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are Black men diagnosed with metastatic prostate cancer.
Not a fit: Patients who do not have metastatic prostate cancer or are not part of the Black male population may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment strategies for Black men with metastatic prostate cancer.
How similar studies have performed: Previous studies using circulating tumor cells for cancer profiling have shown promising results, indicating that this approach may be effective in understanding racial disparities in cancer.
Where this research is happening
Philadelphia, United States
- Thomas Jefferson University — Philadelphia, United States (Active)
Researchers
- Principal investigator: Wang, Chun — Thomas Jefferson University
- Study coordinator: Wang, Chun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.