NIH-funded research R01 grant

Examining how cardiovascular risk factors change throughout adulthood and their link to disease.

Official title: Combining longitudinal cohort studies to examine cardiovascular risk factor trajectories across the adult lifespan and their association with disease

Funded at Northwestern University at Chicago · NIH-10840860 · Data updated 2026-11-12

This study looks at how things like blood pressure and cholesterol change from young adulthood to older age and how these changes can affect heart health, helping people understand their risks and improve prevention strategies for heart disease.

More Cardiovascular Risk research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNorthwestern University at Chicago
NIH-funded
Lab location1 site (Chicago, United States)
Project startJune 15, 2021
Project endMay 31, 2026
Funding year2024
Award (this year)$564,995
NIH project number5R01HL158963-04
Project IDNIH-10840860 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include adults aged 21 and older who are interested in understanding their cardiovascular health and risk factors over time.

Less likely to help

Patients who are under 21 years old or those with pre-existing severe cardiovascular conditions may not benefit directly from this research.

What this research studies

This research investigates how cardiovascular risk factors, such as blood pressure and cholesterol levels, evolve from young adulthood to older age and how these changes relate to the development of cardiovascular diseases (CVD). By combining data from various long-term studies, the project aims to create a comprehensive view of cardiovascular health across different life stages. Patients may benefit from insights into how their risk factors at different ages can influence their heart health later in life, potentially leading to better prevention strategies.

Why it matters

Potential benefit: If successful, this research could provide patients with a clearer understanding of how managing cardiovascular risk factors early in life can reduce their chances of developing heart disease as they age.

How similar studies have gone: Previous research has shown success in using longitudinal data to understand health trajectories, making this approach promising for studying cardiovascular health.

Where this research is happening

  • Northwestern University at Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Siddique, Juned — Northwestern University at Chicago
  • Study coordinator: Siddique, Juned

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.