Examining chest wall movement in people with Parkinson's disease

Ribcage-abdominal movement asynchrony in persons with Parkinsons disease

NIH-funded research Medical University of South Carolina · NIH-10947699

This study looks at how people with Parkinson's disease move their chest while breathing and talking, to see if these movements might be causing speech problems like soft voice, and the goal is to find ways to help improve communication and reduce feelings of loneliness for those affected.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionMedical University of South Carolina NIH-funded
Lab location1 site (Charleston, United States)
Project IDNIH-10947699 on NIH RePORTER

What this research studies

This research investigates how the chest wall movements of individuals with Parkinson's disease are coordinated during breathing and speech. By analyzing data from five existing datasets, the study aims to identify how asynchronous movements may contribute to speech difficulties, particularly hypophonia, which affects a significant number of patients. Understanding these dynamics could lead to improved therapeutic interventions that enhance communication and reduce the social isolation experienced by patients. The research employs a comprehensive analysis of respiratory mechanics to uncover potential new factors influencing speech production.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with Parkinson's disease and experience speech difficulties.

Not a fit: Patients who do not have Parkinson's disease or those without speech-related issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better speech therapy techniques that improve communication for patients with Parkinson's disease.

How similar studies have performed: While studies have explored aspects of respiratory function in Parkinson's disease, this specific focus on chest wall movement dynamics is relatively novel and has not been extensively tested.

Where this research is happening

Charleston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Amyotrophic Lateral Sclerosis Motor Neuron DiseaseBlood Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.