NIH-funded research R21 grant

Examining chemical exposure in East Palestine after a train accident

Official title: Profiling the Post-accident Exposome in East Palestine

Funded at University of Pittsburgh at Pittsburgh · NIH-11013872 · Data updated 2026-11-12

This study is looking at how chemicals from a train derailment in East Palestine, Ohio, have affected the soil, water, and sediment in the area, so we can better understand any health risks for the community.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh
NIH-funded
Lab location1 site (Pittsburgh, United States)
Project startJanuary 22, 2024
Project endDecember 31, 2025
Funding year2025
Award (this year)$187,863
NIH project number5R21ES036033-02
Project IDNIH-11013872 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation or benefit from this research include residents of East Palestine and surrounding communities who may have been exposed to the contaminants.

Less likely to help

Patients who do not reside in or have not been affected by the contamination in the East Palestine area may not receive any benefit from this research.

What this research studies

This research investigates the chemical exposure profiles in communities affected by a train derailment in East Palestine, Ohio. It focuses on monitoring the contamination of soil, water, and sediment due to released chemicals and their by-products. By utilizing both targeted and non-targeted approaches, the study aims to assess the environmental impact and potential health risks associated with these contaminants. The findings will help understand the extent of exposure and inform future health risk assessments.

Why it matters

Potential benefit: If successful, this research could provide critical insights into the health risks associated with chemical exposure from the accident, potentially guiding public health responses and interventions.

How similar studies have gone: Similar research has shown success in assessing environmental exposures and health risks following chemical accidents, indicating that this approach is both relevant and necessary.

Where this research is happening

  • University of Pittsburgh at Pittsburgh
    Pittsburgh, United States
    Active

Researchers

  • Principal investigator: Fabisiak, James P — University of Pittsburgh at Pittsburgh
  • Study coordinator: Fabisiak, James P

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.