Examining cancer risk and mortality in survivors of the World Trade Center disaster
Integrated analysis of cancer risk and mortality in WTC survivors
This study is looking at how the pollution from the World Trade Center disaster might affect cancer risk and survival for people in the local community, especially those who were most impacted, to better understand the long-term health effects of that event.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10994991 on NIH RePORTER |
What this research studies
This research investigates the impact of environmental exposures from the World Trade Center disaster on cancer risk and mortality among local community members. It focuses on understanding how carcinogenic compounds released during the event may lead to somatic mutations and changes in DNA methylation associated with cancer development. The study aims to analyze cancer incidence and mortality rates, particularly among diverse populations affected by the disaster, to gain insights into the long-term health effects of such exposures.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who were exposed to the dust and fumes from the World Trade Center disaster, particularly those from diverse backgrounds.
Not a fit: Patients who were not exposed to the World Trade Center disaster or who do not have a history of cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of cancer risks in WTC survivors, potentially informing better screening and treatment strategies.
How similar studies have performed: Previous studies have shown elevated cancer rates among first responders, indicating that this research builds on established findings but aims to address gaps in diversity and understanding of cancer risks.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Shao, Yongzhao — New York University School of Medicine
- Study coordinator: Shao, Yongzhao
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.