Examining blood flow responses in children with and without autism using brain imaging.

Evaluating cerebrovascular reactivity in autistic and non-autistic children using resting-state functional MRI

NIH-funded research University of California at Davis · NIH-10996712

This study looks at how blood flow in the brains of autistic and non-autistic children works differently, using a safe and painless imaging method, to help us learn more about how their brains connect and function.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of California at Davis NIH-funded
Lab location1 site (Davis, United States)
Project IDNIH-10996712 on NIH RePORTER

What this research studies

This research investigates how blood flow in the brain responds in autistic and non-autistic children by using a non-invasive brain imaging technique called resting-state functional MRI (rsfMRI). The study aims to understand the relationship between blood vessel function and brain connectivity, which may differ in children with autism. By measuring changes in blood flow and brain activity, researchers hope to uncover important insights into the neural mechanisms underlying autism. This could lead to a better understanding of how brain function varies in different populations, particularly in early development.

Who could benefit from this research

Good fit: Ideal candidates for participation include children aged 2 to 12 years, both autistic and non-autistic.

Not a fit: Patients outside the age range of 2 to 12 years or those with conditions unrelated to autism may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of autism and potentially lead to improved diagnostic and therapeutic strategies for affected children.

How similar studies have performed: Previous research has shown promise in using functional MRI to study brain connectivity in autism, but this specific approach to cerebrovascular reactivity is relatively novel.

Where this research is happening

Davis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.