Examining a new therapy for adolescents with low weight eating disorders

A Confirmatory Efficacy Study of Interoceptive Exposure for Adolescents with Low Weight Eating Disorders

NIH-funded research Icahn School of Medicine at Mount Sinai · NIH-11013332

This study is testing a new therapy called family-based interoceptive exposure (FBT-E) to see if it helps teenagers with low weight eating disorders, like anorexia, feel better and gain weight compared to the usual family-based therapy.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11013332 on NIH RePORTER

What this research studies

This research investigates a novel therapy called family-based interoceptive exposure (FBT-E) for adolescents suffering from low weight eating disorders like anorexia nervosa. The study aims to compare the effectiveness of FBT-E against traditional family-based therapy (FBT) in improving weight and reducing eating disorder symptoms over a 12-month period. Participants will be adolescents aged 12-18, and the research will involve a randomized controlled trial to assess both short-term and long-term outcomes. The approach focuses on reducing food avoidance and enhancing body awareness through targeted therapeutic techniques.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 12-18 who are diagnosed with low weight eating disorders such as anorexia nervosa.

Not a fit: Patients who are outside the age range of 12-18 or those not diagnosed with low weight eating disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatment options for adolescents with low weight eating disorders, improving their overall health and quality of life.

How similar studies have performed: Preliminary data from earlier studies suggest that similar therapeutic approaches have shown promise, indicating potential for success in this confirmatory trial.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.