Evaluating vaccines for the H5N1 influenza virus
Official title: Clinical Trails to Evaluate H5N1 Influenza Variant Vaccines
Funded at Leidos Biomedical Research, INC. · NIH-11210622 · Data updated 2026-11-12
This study is looking for people to help test new vaccines for the H5N1 bird flu virus to see how safe and effective they are, so we can find the best options to protect against this virus.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Leidos Biomedical Research, INC. NIH-funded |
| Lab location | 1 site (Frederick, United States) |
| Project start | September 9, 2024 |
| Project end | September 8, 2027 |
| Funding year | 2024 |
| Award (this year) | $7,985,002 |
| NIH project number | 75N91019D00024-0-759102400032-1 |
| Project ID | NIH-11210622 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation include healthy adults and individuals at risk of exposure to H5N1, such as those working with birds or in agricultural settings.
✕Less likely to help
Patients who are not at risk of H5N1 exposure or those with certain health conditions that exclude them from vaccine trials may not benefit from this research.
What this research studies
This research focuses on the ongoing public health challenge posed by the H5N1 influenza virus, which primarily affects birds but can also infect other animals, including cattle. The project aims to conduct phase 1 and phase 2 clinical trials to evaluate the safety and effectiveness of various H5N1 vaccine candidates. By generating critical data, the research will help determine which vaccine candidates should proceed to advanced development. Patients may have the opportunity to participate in these trials, contributing to the fight against this serious viral threat.
Why it matters
Potential benefit: If successful, this research could lead to effective vaccines that protect against H5N1 influenza, potentially saving lives and preventing outbreaks.
How similar studies have gone: Previous research on influenza vaccines has shown success in developing effective vaccines for other strains, indicating a promising potential for this approach.
Where this research is happening
-
Leidos Biomedical Research, INC.
Frederick, United States Active
Researchers
- Principal investigator: Engel, Theresa — Leidos Biomedical Research, INC.
- Study coordinator: Engel, Theresa
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.