Evaluating vaccines for the H5N1 influenza virus

Clinical Trails to Evaluate H5N1 Influenza Variant Vaccines

NIH-funded research Leidos Biomedical Research, INC. · NIH-11210622

This study is looking for people to help test new vaccines for the H5N1 bird flu virus to see how safe and effective they are, so we can find the best options to protect against this virus.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionLeidos Biomedical Research, INC. NIH-funded
Lab location1 site (Frederick, United States)
Project IDNIH-11210622 on NIH RePORTER

What this research studies

This research focuses on the ongoing public health challenge posed by the H5N1 influenza virus, which primarily affects birds but can also infect other animals, including cattle. The project aims to conduct phase 1 and phase 2 clinical trials to evaluate the safety and effectiveness of various H5N1 vaccine candidates. By generating critical data, the research will help determine which vaccine candidates should proceed to advanced development. Patients may have the opportunity to participate in these trials, contributing to the fight against this serious viral threat.

Who could benefit from this research

Good fit: Ideal candidates for participation include healthy adults and individuals at risk of exposure to H5N1, such as those working with birds or in agricultural settings.

Not a fit: Patients who are not at risk of H5N1 exposure or those with certain health conditions that exclude them from vaccine trials may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to effective vaccines that protect against H5N1 influenza, potentially saving lives and preventing outbreaks.

How similar studies have performed: Previous research on influenza vaccines has shown success in developing effective vaccines for other strains, indicating a promising potential for this approach.

Where this research is happening

Frederick, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Disease Outbreaks
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.