Evaluating uterine fibroids using advanced ultrasound techniques before and after a non-surgical treatment.
Official title: Evaluation of Uterine Fibroids by Contrast Enhanced Ultrasound (CEUS) and Subharmonic-Aided Pressure Estimation (SHAPE) Pre and Post Uterine Artery Embolization (UAE)
Funded at Thomas Jefferson University · NIH-10951023 · Data updated 2026-11-12
This study is looking at how well new ultrasound techniques can help women with uterine fibroids see how their condition changes before and after a common treatment, aiming to offer a more affordable and easier option than traditional MRI scans.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Thomas Jefferson University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $195,000 |
| NIH project number | 1R21HD116236-01 |
| Project ID | NIH-10951023 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include women diagnosed with uterine fibroids, particularly those who are preparing for or have undergone uterine artery embolization.
✕Less likely to help
Patients who do not have uterine fibroids or those who are not candidates for uterine artery embolization may not benefit from this research.
What this research studies
This research investigates the effectiveness of using contrast-enhanced ultrasound (CEUS) and subharmonic-aided pressure estimation (SHAPE) to evaluate uterine fibroids in women before and after undergoing uterine artery embolization (UAE). The study aims to provide a cost-effective and non-invasive alternative to the traditional MRI imaging method, which is often expensive and less accessible. By utilizing advanced ultrasound techniques, the research seeks to improve the accuracy of diagnosing and monitoring the treatment of uterine fibroids, particularly in populations where they are more prevalent. Patients will be assessed for both structural and functional characteristics of fibroids using these innovative imaging modalities.
Why it matters
Potential benefit: If successful, this research could provide a more accessible and affordable method for diagnosing and monitoring uterine fibroids, improving patient outcomes.
How similar studies have gone: Previous research has shown promise in using ultrasound techniques for similar diagnostic purposes, indicating that this approach may lead to meaningful advancements in patient care.
Where this research is happening
-
Thomas Jefferson University
Philadelphia, United States Active
Researchers
- Principal investigator: Machado, Priscilla — Thomas Jefferson University
- Study coordinator: Machado, Priscilla
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.