Evaluating treatments to reduce cervical cancer risk in HIV-positive women in Mozambique
A Randomized Clinical Trial to Assess the Effectiveness of Ablative Treatments for Cervical Cancer Risk Reduction in HIV+ Women living in Mozambique
This study is looking at two different treatments to help lower the chances of cervical cancer in women with HIV in Mozambique, and it's for women aged 25-49 who are already visiting clinics for their HIV care.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10687168 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of two ablative treatments, gas-based cryotherapy and thermocoagulation, for reducing the risk of cervical cancer in women living with HIV in Mozambique. The study will involve a randomized clinical trial with 5,014 eligible women aged 25-49 who will be recruited during their routine HIV care visits. Participants will be screened for cervical abnormalities and treated accordingly, with the aim of determining the best approach to prevent cervical cancer in this high-risk population.
Who could benefit from this research
Good fit: Ideal candidates for this research are women aged 25-49 living with HIV in Maputo, Mozambique, who are attending routine HIV care.
Not a fit: Patients who are not living with HIV or those outside the specified age range may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly lower the incidence of cervical cancer among HIV-positive women in Mozambique.
How similar studies have performed: Previous research has shown promising results with ablative treatments for cervical cancer prevention, indicating potential success for this approach.
Where this research is happening
Houston, United States
- University of Tx Md Anderson Can Ctr — Houston, United States (Active)
Researchers
- Principal investigator: Schmeler, Kathleen — University of Tx Md Anderson Can Ctr
- Study coordinator: Schmeler, Kathleen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.