Evaluating treatments for open-angle glaucoma in diverse patient populations
Designing a Pragmatic Registry-based Randomized Controlled Trial for Open-Angle Glaucoma Treatment in the US
This study is looking at how well a special laser treatment works compared to eye drops for people with open-angle glaucoma, and it's open to a diverse group of patients to make sure the results reflect everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10867985 on NIH RePORTER |
What this research studies
This research aims to investigate the effectiveness of selective laser trabeculoplasty (SLT) compared to medications for treating open-angle glaucoma in a diverse group of patients. By utilizing a pragmatic registry-based randomized controlled trial approach, the study seeks to recruit participants from various racial and ethnic backgrounds, as well as those with different levels of English proficiency and health insurance status. This method allows for a more accurate representation of the US population and aims to provide high-quality evidence on treatment efficacy in real-world settings. The study will focus on patients who have recently been diagnosed with open-angle glaucoma and may have other eye conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have recently been diagnosed with open-angle glaucoma and represent a variety of racial, ethnic, and socioeconomic backgrounds.
Not a fit: Patients who do not have open-angle glaucoma or those who have advanced glaucoma requiring immediate intervention may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for open-angle glaucoma that are effective across diverse populations.
How similar studies have performed: Previous research has shown that pragmatic registry-based trials can effectively recruit diverse populations and yield valuable insights, indicating a promising approach for this study.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Sun, Catherine Qing — University of California, San Francisco
- Study coordinator: Sun, Catherine Qing
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.