Evaluating treatment options for brain hemorrhage and their effects on cognitive decline

REpeated ASseSsmEnt of SurvivorS in ICH (REASSESS ICH)

NIH-funded research Johns Hopkins University · NIH-11005034

This study is looking at how different ways to treat bleeding in the brain can impact the long-term thinking and memory skills of patients, especially older adults, to see if less invasive surgery helps them recover better than standard care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11005034 on NIH RePORTER

What this research studies

This research investigates how different treatment strategies for spontaneous intracerebral hemorrhage (ICH) affect long-term cognitive health in patients. It involves long-term assessments of cognitive, functional, and neuropsychiatric performance in ICH survivors, comparing minimally invasive surgical techniques to standard care. The study aims to determine if reducing hematoma volume through surgery can lower the risk of cognitive decline in aging patients. Participants will be monitored through structured interviews to gather data on their recovery and cognitive function over time.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have experienced a spontaneous intracerebral hemorrhage and are at risk for cognitive decline.

Not a fit: Patients who have not experienced an intracerebral hemorrhage or those with pre-existing severe cognitive impairment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies that enhance cognitive outcomes for patients recovering from brain hemorrhages.

How similar studies have performed: Previous studies have shown promising results with minimally invasive surgical techniques in improving outcomes for ICH patients, suggesting that this approach may be effective.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.