Evaluating treatment for ADHD in children with Down syndrome
Evaluating Assessment and Medication Treatment of ADHD in Children with Down Syndrome
This study is looking at how well stimulant medication works and how safe it is for treating ADHD in children with Down syndrome, ages 6 to 17, to help make sure they get the right care they need.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-10754339 on NIH RePORTER |
What this research studies
This research investigates the effectiveness and safety of stimulant medication for treating Attention Deficit Hyperactivity Disorder (ADHD) in children with Down syndrome. It aims to address the under-treatment of ADHD in this population by conducting a randomized clinical trial that includes children aged 6-17 years. Participants will undergo a double-blind trial, where they will receive either the medication or a placebo, followed by long-term follow-up assessments. The study seeks to clarify diagnostic challenges and evaluate the potential cardiac safety concerns associated with stimulant use in children with Down syndrome.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 6-17 years who have both Down syndrome and a diagnosis of ADHD.
Not a fit: Patients who do not have Down syndrome or those without a diagnosis of ADHD are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for children with Down syndrome who also have ADHD, enhancing their quality of life and developmental outcomes.
How similar studies have performed: This research is novel as there have been no prior clinical trials specifically examining the safety and efficacy of stimulant medication in children with Down syndrome and ADHD.
Where this research is happening
Cincinnati, United States
- Cincinnati Childrens Hosp Med Ctr — Cincinnati, United States (Active)
Researchers
- Principal investigator: Esbensen, Anna J. — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: Esbensen, Anna J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.