Evaluating Tirzepatide for treating alcohol use disorder and obesity in adults
Phase II Evaluation of Tirzepatide in Adults with Alcohol Use Disorder and Overweight or Obesity
['FUNDING_R21'] · UNIVERSITY OF SOUTHERN CALIFORNIA · NIH-10999946
This study is looking at how well Tirzepatide, a new weight loss medication, can help adults who are overweight or obese and also have trouble with alcohol use, by seeing if it can reduce their drinking and help them lose weight for better health.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF SOUTHERN CALIFORNIA (nih funded) |
| Locations | 1 site (Los Angeles, UNITED STATES) |
| Trial ID | NIH-10999946 on ClinicalTrials.gov |
What this research studies
This research investigates the effects of Tirzepatide, a medication recently approved for weight loss, on adults who struggle with alcohol use disorder and are overweight or obese. The study aims to determine if this dual-action drug can help reduce alcohol consumption while also promoting weight loss, thereby improving overall health outcomes. Participants will be monitored for changes in their alcohol intake, body weight, and cardiovascular health over the course of the study. The approach combines clinical assessments with patient-reported outcomes to evaluate the medication's effectiveness.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who have both alcohol use disorder and are classified as overweight or obese.
Not a fit: Patients who do not have alcohol use disorder or who are not overweight or obese may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new treatment option that addresses both alcohol use disorder and obesity, potentially improving health and quality of life for affected individuals.
How similar studies have performed: Previous research has shown promising results with GLP-1 receptor agonists in reducing alcohol consumption and aiding weight loss, suggesting that this approach may be effective.
Where this research is happening
Los Angeles, UNITED STATES
- UNIVERSITY OF SOUTHERN CALIFORNIA — Los Angeles, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HENDERSHOT, CHRISTIAN S — UNIVERSITY OF SOUTHERN CALIFORNIA
- Study coordinator: HENDERSHOT, CHRISTIAN S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.