Evaluating the safety of new drugs for children
TreeScan to Evaluate the Safety of New Drugs in Pediatric Populations
This study is testing a new way to check if medications are safe for kids, using health data to look at possible side effects, so that doctors can make better choices when treating children.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10851994 on NIH RePORTER |
What this research studies
This research focuses on developing a new method called TreeScan to assess the safety of medications specifically for pediatric patients. It aims to address the lack of systematic monitoring of drug safety in children, who often receive medications without sufficient evidence of their safety and effectiveness. By utilizing healthcare data, the study will evaluate multiple potential adverse outcomes simultaneously, ensuring that new pediatric drugs are monitored closely. This approach seeks to provide better safety information for medications used in children, ultimately improving treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include children aged 0-11 years who may be prescribed new medications.
Not a fit: Patients who are not children or those who do not require new medications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer medication practices for children, reducing the risks associated with off-label drug use.
How similar studies have performed: Other research has shown success in using data-driven approaches for drug safety monitoring in adults, but this specific focus on pediatric populations is novel.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Wang, Shirley — Brigham and Women's Hospital
- Study coordinator: Wang, Shirley
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.