Evaluating the effects of certain flame retardants on rats during development.
Official title: Conduct of studies to evaluate the subchronic and developmental neurotoxicity of isopropylated phenol phosphate (IPP) and triphenyl phosphate (TPHP)in rats (after perinatal exposure)
Funded at Battelle Centers/pub Hlth Res & Evaluatn · NIH-11216074 · Data updated 2026-11-12
This study is looking at how certain chemicals, found in some products, might affect the health and development of baby rats when their mothers are pregnant or nursing, to help keep people safe from harmful substances.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Battelle Centers/pub Hlth Res & Evaluatn NIH-funded |
| Lab location | 1 site (Columbus, United States) |
| Project start | September 16, 2024 |
| Project end | September 15, 2025 |
| Funding year | 2024 |
| Award (this year) | $503,295 |
| NIH project number | 75N96024C00005-0-9999-6 |
| Project ID | NIH-11216074 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals concerned about exposure to flame retardants and their potential health effects, particularly pregnant women and families with young children.
✕Less likely to help
Patients who are not exposed to flame retardants or those without concerns about chemical exposure may not receive direct benefits from this research.
What this research studies
This research investigates the potential neurotoxic effects of isopropylated phenol phosphate (IPP) and triphenyl phosphate (TPHP) on rats, focusing on exposure during critical developmental periods such as gestation and lactation. The study involves administering these chemicals through dosed feed to assess their impact on health and development. By understanding how these substances affect rats, researchers aim to gather data that can inform public health decisions regarding chemical safety and environmental exposure. The findings will contribute to risk assessment efforts and help identify hazardous chemicals in consumer products.
Why it matters
Potential benefit: If successful, this research could lead to improved safety regulations regarding the use of flame retardants in consumer products, ultimately protecting public health.
How similar studies have gone: Previous research has shown that toxicity testing of similar chemicals has successfully identified hazardous effects, supporting the need for ongoing evaluation of new flame retardants.
Where this research is happening
-
Battelle Centers/pub Hlth Res & Evaluatn
Columbus, United States Active
Researchers
- Principal investigator: Fallacara, Dawn — Battelle Centers/pub Hlth Res & Evaluatn
- Study coordinator: Fallacara, Dawn
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.