Evaluating the effects of cannabis terpenes on neuropathic pain relief

Therapeutic and Mechanistic Evaluation of Cannabis sativa Terpenes in Neuropathic Pain

['FUNDING_R01'] · UNIVERSITY OF ARIZONA · NIH-11071994

This study is looking at how certain natural compounds in cannabis, called terpenes, might help relieve nerve pain that doesn't respond well to regular pain medications, with the hope of finding a safer option for managing pain.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF ARIZONA (nih funded)
Locations1 site (TUCSON, UNITED STATES)
Trial IDNIH-11071994 on ClinicalTrials.gov

What this research studies

This research investigates how specific compounds found in cannabis, known as terpenes, can help alleviate neuropathic pain, which is often resistant to traditional opioid treatments. The study aims to understand the mechanisms by which these terpenes may provide pain relief and enhance the effectiveness of cannabinoids like THC. By conducting detailed analyses and experiments, the research seeks to establish a clearer understanding of how these natural compounds can be utilized in pain management, potentially offering a safer alternative to opioids.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing chronic neuropathic pain who are seeking alternative treatment options.

Not a fit: Patients who do not have neuropathic pain or those who are not interested in cannabis-based therapies may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new, effective pain management options for patients suffering from neuropathic pain without the risks associated with opioid use.

How similar studies have performed: While there is limited evidence on the efficacy of cannabis terpenes, previous studies have shown promise in using cannabinoids for pain relief, suggesting potential for success in this novel approach.

Where this research is happening

TUCSON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: addictive disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.