Evaluating the effects of cannabis terpenes on neuropathic pain relief
Official title: Therapeutic and Mechanistic Evaluation of Cannabis sativa Terpenes in Neuropathic Pain
Funded at University of Arizona · NIH-11071994 · Data updated 2026-11-12
This study is looking at how certain natural compounds in cannabis, called terpenes, might help relieve nerve pain that doesn't respond well to regular pain medications, with the hope of finding a safer option for managing pain.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project start | July 1, 2021 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $286,922 |
| NIH project number | 5R01AT011517-05 |
| Project ID | NIH-11071994 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing chronic neuropathic pain who are seeking alternative treatment options.
✕Less likely to help
Patients who do not have neuropathic pain or those who are not interested in cannabis-based therapies may not benefit from this research.
What this research studies
This research investigates how specific compounds found in cannabis, known as terpenes, can help alleviate neuropathic pain, which is often resistant to traditional opioid treatments. The study aims to understand the mechanisms by which these terpenes may provide pain relief and enhance the effectiveness of cannabinoids like THC. By conducting detailed analyses and experiments, the research seeks to establish a clearer understanding of how these natural compounds can be utilized in pain management, potentially offering a safer alternative to opioids.
Why it matters
Potential benefit: If successful, this research could lead to new, effective pain management options for patients suffering from neuropathic pain without the risks associated with opioid use.
How similar studies have gone: While there is limited evidence on the efficacy of cannabis terpenes, previous studies have shown promise in using cannabinoids for pain relief, suggesting potential for success in this novel approach.
Where this research is happening
-
University of Arizona
Tucson, United States Active
Researchers
- Principal investigator: Streicher, John Michael — University of Arizona
- Study coordinator: Streicher, John Michael
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.