Evaluating the effects of cannabis compounds on nerve pain from chemotherapy
A Pilot Study to Evaluate the Benefits of Phytocannabinoids for the Treatment of Chronic Chemotherapy-Induced Peripheral Neuropathy
This study is looking at whether CBD and THC can help cancer survivors who have nerve pain from chemotherapy feel better, and if you join, you might receive one of these treatments or a placebo over eight weeks to see how it helps with symptoms like tingling and pain.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beckman Research Institute/city of Hope NIH-funded |
| Lab location | 1 site (Duarte, United States) |
| Project ID | NIH-10512235 on NIH RePORTER |
What this research studies
This research investigates the potential benefits of phytocannabinoids, specifically cannabidiol (CBD) and tetrahydrocannabinol (THC), in treating chronic chemotherapy-induced peripheral neuropathy in cancer survivors. Participants, including breast and colon cancer survivors, will be randomly assigned to receive either CBD, a combination of CBD and THC, or a placebo over an 8-week period. The study aims to gather data on how these compounds may alleviate symptoms such as tingling, numbness, and pain, which significantly impact the quality of life for many cancer survivors. By addressing the lack of information on cannabis use in this context, the research seeks to provide valuable insights for patients and healthcare providers.
Who could benefit from this research
Good fit: Ideal candidates for this research are adult cancer survivors, particularly those who have experienced chronic nerve pain following chemotherapy.
Not a fit: Patients who do not have a history of chemotherapy-induced peripheral neuropathy or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could offer new treatment options for cancer survivors suffering from debilitating nerve pain.
How similar studies have performed: While the use of cannabis for pain management is gaining popularity, this specific approach to treating chemotherapy-induced neuropathy is relatively novel and has limited prior research backing.
Where this research is happening
Duarte, United States
- Beckman Research Institute/city of Hope — Duarte, United States (Active)
Researchers
- Principal investigator: Lee, Richard T — Beckman Research Institute/city of Hope
- Study coordinator: Lee, Richard T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.