Evaluating the effects of an artificial pancreas on adolescents with Type 1 diabetes
Artificial Pancreas - Adolescent Physiology and Psychology Longitudinal Evaluation (A.P. APPLE)
This study is looking at how an artificial pancreas can help teenagers with Type 1 diabetes, ages 11 to 15, better manage their blood sugar levels during puberty, while also considering how family and friends might affect their diabetes care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project ID | NIH-10829344 on NIH RePORTER |
What this research studies
This research investigates how an artificial pancreas system can help manage blood sugar levels in adolescents with Type 1 diabetes, particularly during the challenging ages of 11 to 15 years. The study will follow participants over two years, assessing both physiological changes, such as insulin resistance, and psychosocial factors like family dynamics and peer influence. By comparing the artificial pancreas system to standard care, the research aims to understand how these interventions can improve diabetes management during puberty. Participants will undergo various assessments, including tests to measure insulin resistance in different body tissues.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents aged 11 to 15 years diagnosed with Type 1 diabetes.
Not a fit: Patients outside the age range of 11 to 15 years or those without Type 1 diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved blood sugar control and overall health outcomes for adolescents with Type 1 diabetes.
How similar studies have performed: Previous research has shown promising results with artificial pancreas systems in managing diabetes, indicating potential for success in this approach.
Where this research is happening
Charlottesville, United States
- University of Virginia — Charlottesville, United States (Active)
Researchers
- Principal investigator: Deboer, Mark Daniel — University of Virginia
- Study coordinator: Deboer, Mark Daniel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.