Evaluating the effectiveness of vaccines for respiratory viruses in Cleveland.
Official title: RFA-IP-22-004, CORVETS - Cleveland Ohio Respiratory Viruses Vaccines Effectiveness across Traditional Risk Factors and Social Determinants of Health
Funded at University Hospitals of Cleveland · NIH-10908242 · Data updated 2026-11-12
This study is looking at how well vaccines for respiratory viruses like the flu and COVID-19 work in preventing sickness among different groups of people in Cleveland, and it’s for anyone who has had these kinds of illnesses.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University Hospitals of Cleveland NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | September 30, 2022 |
| Project end | September 29, 2027 |
| Funding year | 2024 |
| Award (this year) | $2,600,000 |
| NIH project number | 5U01IP001181-03 |
| Project ID | NIH-10908242 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation include individuals of all ages who have experienced acute respiratory viral illnesses and are seeking care in ambulatory settings.
✕Less likely to help
Patients who do not have respiratory viral illnesses or those who are not seeking care in ambulatory settings may not benefit from this research.
What this research studies
This research investigates how effective vaccines for respiratory viruses, including influenza and COVID-19, are in preventing acute illnesses among diverse populations in Cleveland. The study will recruit at least 1,000 patients annually who have experienced respiratory viral illnesses and will utilize advanced testing technologies to analyze viral variants. By examining both individual and household factors, the research aims to understand how traditional risk factors and social determinants of health impact vaccine effectiveness. Patients will be monitored in ambulatory settings to gather comprehensive data on their health outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccine strategies that enhance protection against respiratory viruses for various populations.
How similar studies have gone: Previous research has shown success in evaluating vaccine effectiveness for respiratory viruses, indicating that this approach is grounded in established methodologies.
Where this research is happening
-
University Hospitals of Cleveland
Cleveland, United States Active
Researchers
- Principal investigator: Saade, Elie — University Hospitals of Cleveland
- Study coordinator: Saade, Elie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.