Evaluating the effectiveness of new RSV prevention methods for infants
Official title: Real-World Effectiveness of Perinatal RSV Immunoprophylaxis
Funded at Yale University · NIH-10997417 · Data updated 2026-11-12
This study is looking at new ways to help protect babies from respiratory syncytial virus (RSV), which can make them very sick, and it’s for families with young children who want to know how well these new treatments work in everyday life.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | December 8, 2023 |
| Project end | October 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $805,130 |
| NIH project number | 5R01AI179874-02 |
| Project ID | NIH-10997417 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include infants under one year of age, particularly those born to mothers who receive the new immunoprophylactic treatments.
✕Less likely to help
Patients who are older than one year or those who do not have access to the new immunoprophylactic treatments may not benefit from this research.
What this research studies
This research investigates the effectiveness of new immunoprophylactic agents designed to protect infants from respiratory syncytial virus (RSV), a leading cause of hospitalization in young children. The study will involve a large-scale case-control approach, integrating various data types such as clinical and demographic information to assess how well these new prevention strategies work in real-world settings. By actively monitoring both inpatient and outpatient clinical sites, the research aims to provide valuable insights into the risks and benefits of these new treatments for infants and their families.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of RSV-related hospitalizations and deaths in infants.
How similar studies have gone: Previous research has shown promise in similar approaches to RSV prevention, indicating potential for success with these new immunoprophylactic strategies.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Oliveira, Carlos Rafael — Yale University
- Study coordinator: Oliveira, Carlos Rafael
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.