Evaluating the effectiveness of a toxin in animal models for vaccine development
Official title: Task V18: STUDY TO EVALUATE THE EFFICACY OF TOXIN IN ANIMAL MODEL
Funded at Battelle Centers/pub Hlth Res & Evaluatn · NIH-10923430 · Data updated 2026-11-12
This study is looking at a new toxin to help create vaccines that could protect us from serious infections, especially those that might be used in bioterrorism, and while it's being tested on animals now, it could lead to safer treatments for people in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Battelle Centers/pub Hlth Res & Evaluatn NIH-funded |
| Lab location | 1 site (Columbus, United States) |
| Project start | August 1, 2023 |
| Project end | October 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $1,139,090 |
| NIH project number | 272201800013I-0-759302300002-1 |
| Project ID | NIH-10923430 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would be individuals at risk of exposure to infectious diseases or those in high-risk environments.
✕Less likely to help
Patients who are not at risk for infectious diseases or bioterrorism threats may not receive direct benefits from this research.
What this research studies
This research investigates the efficacy of a toxin using animal models to support the development of vaccines and biologics against infectious diseases, particularly those that could be used in bioterrorism. The approach includes a range of services from early feasibility studies to the necessary testing and validation required for regulatory submissions. Patients may benefit indirectly as the findings could lead to new vaccines that protect against serious infectious diseases. The research also involves safety and toxicology studies to ensure that any new treatments are safe for human use.
Why it matters
Potential benefit: If successful, this research could lead to the development of new vaccines that protect against emerging infectious diseases and bioterrorism threats.
How similar studies have gone: Previous research has shown success in developing vaccines through similar methodologies, indicating a promising approach.
Where this research is happening
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Battelle Centers/pub Hlth Res & Evaluatn
Columbus, United States Active
Researchers
- Principal investigator: Rudge, Thomas — Battelle Centers/pub Hlth Res & Evaluatn
- Study coordinator: Rudge, Thomas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.