NIH-funded research R01 grant

Evaluating the economic impact of a prevention system for youth resilience

Official title: Investing in Prevention Infrastructure: Economic Evaluation of the PROSPER System

Funded at Pennsylvania State University, the · NIH-11056807 · Data updated 2026-11-12

This study looks at how a program called PROSPER helps young people in rural areas by providing support to prevent substance misuse, and it aims to find out if these programs are worth the cost and how they can be even more effective as these teens grow up.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionPennsylvania State University, the
NIH-funded
Lab location1 site (University Park, United States)
Project startMay 15, 2023
Project endMarch 31, 2028
Funding year2025
Award (this year)$693,536
NIH project number5R01DA057996-03
Project IDNIH-11056807 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include adolescents aged 12-20 who are at risk for substance misuse and live in rural communities.

Less likely to help

Patients who are not adolescents or those living in urban areas may not receive direct benefits from this research.

What this research studies

This research investigates the economic effects of the PROSPER system, which focuses on delivering evidence-based preventive interventions to youth in rural communities. By analyzing data from a previous trial that involved over 12,000 adolescents, the study aims to understand how these interventions can lead to long-term benefits in reducing substance misuse and enhancing community resilience. The research will assess the economic implications of these interventions as participants transition into adulthood, providing insights into the cost-effectiveness of prevention strategies. Additionally, it will explore how local implementation factors can affect the success of these programs.

Why it matters

Potential benefit: If successful, this research could lead to more effective and economically viable prevention programs that reduce substance misuse among youth.

How similar studies have gone: Previous research on the PROSPER system has shown success in reducing substance misuse among participants, indicating a promising foundation for this economic evaluation.

Where this research is happening

  • Pennsylvania State University, the
    University Park, United States
    Active

Researchers

  • Principal investigator: Crowley, Daniel Max — Pennsylvania State University, the
  • Study coordinator: Crowley, Daniel Max

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.